Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8930335 | 0.84 | GRIN1 (0.38) | GRIN1 | |
| SCHEMBL7470542 | 0.77 | GRIN1 (0.39) | GRIN1 | |
| SCHEMBL8650855 | 0.77 | GRIN1 (0.42) | GRIN1 | |
| SCHEMBL8524293 | 0.77 | HRH4 (0.30) | — | |
| SCHEMBL8525538 | 0.76 | GRIN1 (0.56) | GRIN1 | |
| SCHEMBL7472397 | 0.76 | GRIN1 (0.35) | GRIN1 | |
| SCHEMBL7470510 | 0.73 | RAB9A (0.46) | GRIN1POLB | |
| SCHEMBL7471934 | 0.73 | GRIN1 (0.50) | GRIN1 | |
| SCHEMBL7476576 | 0.73 | GRIN1 (0.35) | GRIN1 | |
| SCHEMBL8488510 | 0.72 | GRIN1 (0.49) | GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863917-A | ANXIOLYTIC AGENT, ANTICONVULSANTS, ANALGESICS AND NEUROPROTECTIVES. | PFIZER, INC. (US) | 1999-01-26 | — | — | US | disclosed |
| EP-0792874-A1 | Quinoxaline derivatives useful in therapy | Pfizer Limited (GB) | 1997-09-03 | — | — | EP | disclosed |