Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 2/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.45 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.44 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.44 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9140781 | 0.89 | SLC6A12 (0.58) | SLC6A12MCHR1BCHEACHEPRKAA2 | |
| SCHEMBL9140098 | 0.88 | SLC6A12 (0.55) | SLC6A12MCHR1BCHEACHEPRKAA2 | |
| SCHEMBL9141561 | 0.88 | SLC6A12 (0.48) | SLC6A12MCHR1BCHEACHEPRKAA2 | |
| Trifluoroacetic Acid SCHEMBL8469973 | 0.86 | SLC6A12 (0.46) | SLC6A12MCHR1BCHEACHEPRKAA2 | |
| SCHEMBL9137922 | 0.86 | SLC6A12 (0.48) | SLC6A12MCHR1BCHEACHEPRKAA2 | |
| SCHEMBL6573538 | 0.86 | SLC6A12 (0.55) | SLC6A12MCHR1BCHEACHEPRKAA2 | |
| SCHEMBL9145344 | 0.86 | SLC6A12 (0.53) | SLC6A12MCHR1BCHEACHEPRKAA2 | |
| SCHEMBL6570012 | 0.86 | SLC6A12 (0.53) | SLC6A12MCHR1BCHEACHEPRKAA2 | |
| SCHEMBL6571119 | 0.85 | SLC6A12 (0.54) | SLC6A12MCHR1BCHEACHEPRKAA2 | |
| SCHEMBL9138847 | 0.84 | DRD4 (0.58) | SLC6A12MCHR1BCHEACHEPRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5438064-A | For suppressing the binding of bradykinins to pain receptors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-08-01 | — | — | US | claimed |
| US-5952346-A | INHIBITS THE ACTIONS OF THE ALZHEIMER'S PROTEIN AMYLOID (BETA/A4) IN ISOLATED ENDOTHELIAL CELLS; QUINOLINE DERIVATIVES | HOECHST MARION ROUSSEL DEUTSCHLAND GMBH (DE) | 1999-09-14 | — | — | US | disclosed |
| US-5438064-A | For suppressing the binding of bradykinins to pain receptors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-08-01 | — | — | US | disclosed |