Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 2/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.47 |
| ▸ | JAK1 | P23458 | 2/20 | 0.44 |
| ▸ | JAK3 | P52333 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570012 | 0.91 | SLC6A12 (0.53) | SLC6A12MCHR1JAK1JAK3JAK2 | |
| SCHEMBL9145344 | 0.91 | SLC6A12 (0.53) | SLC6A12MCHR1JAK1JAK3JAK2 | |
| SCHEMBL9140781 | 0.90 | SLC6A12 (0.58) | SLC6A12MCHR1SIGMAR1ACHEBCHE | |
| SCHEMBL6573538 | 0.89 | SLC6A12 (0.55) | SLC6A12MCHR1JAK1JAK3JAK2 | |
| SCHEMBL6571119 | 0.88 | SLC6A12 (0.54) | SLC6A12MCHR1JAK1JAK3JAK2 | |
| SCHEMBL9141561 | 0.87 | SLC6A12 (0.48) | SLC6A12MCHR1JAK1JAK3JAK2 | |
| SCHEMBL9140098 | 0.86 | SLC6A12 (0.55) | SLC6A12MCHR1SIGMAR1ACHEBCHE | |
| SCHEMBL8524472 | 0.86 | SLC6A12 (0.48) | SLC6A12MCHR1SIGMAR1ACHEBCHE | |
| SCHEMBL9141810 | 0.85 | DRD4 (0.54) | SLC6A12MCHR1JAK1JAK3SIGMAR1 | |
| SCHEMBL9138847 | 0.85 | DRD4 (0.58) | SLC6A12MCHR1JAK1JAK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5438064-A | For suppressing the binding of bradykinins to pain receptors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-08-01 | — | — | US | claimed |
| US-5438064-A | For suppressing the binding of bradykinins to pain receptors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-08-01 | — | — | US | disclosed |