Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.54 |
| ▸ | AXL | P30530 | 1/20 | 0.54 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.54 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.54 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523780 | 0.82 | CYP19A1 (0.48) | CYP19A1RAB9ANPC1MAPTKDM4E | |
| SCHEMBL13028349 | 0.80 | CYP1A2 (0.68) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL8525110 | 0.75 | CDK5 (0.42) | CYP19A1RAB9ANPC1MAPTKDM4E | |
| SCHEMBL8524764 | 0.74 | CYP19A1 (0.45) | CYP19A1RAB9ANPC1MAPTKDM4E | |
| SCHEMBL6196239 | 0.73 | CYP19A1 (1.00) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL4265366 | 0.72 | MAPT (0.69) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL21318943 | 0.72 | CYP19A1 (0.56) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL4264187 | 0.71 | CYP19A1 (0.53) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL8525270 | 0.71 | SMN1; SMN2 (0.70) | CYP19A1RAB9ANPC1MAPTKDM4E | |
| SCHEMBL4264617 | 0.70 | CYP19A1 (0.53) | CYP19A1AXLPBRM1MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |