Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 13/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 13/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523935 | 0.81 | NPC1 (0.44) | CDK5CDK5R1NPC1RAB9AKDM4E | |
| SCHEMBL8524244 | 0.78 | CDK5 (0.38) | CDK5CDK5R1NPC1RAB9AKDM4E | |
| SCHEMBL8524612 | 0.75 | CYP19A1 (0.54) | NPC1RAB9AKDM4ESMN1; SMN2CYP19A1 | |
| SCHEMBL8523719 | 0.74 | CDK5 (0.44) | CDK5CDK5R1NPC1RAB9AKDM4E | |
| SCHEMBL8523780 | 0.73 | CYP19A1 (0.48) | CDK5CDK5R1NPC1RAB9AKDM4E | |
| SCHEMBL8524764 | 0.71 | CYP19A1 (0.45) | CDK5CDK5R1NPC1RAB9AKDM4E | |
| SCHEMBL8525270 | 0.69 | SMN1; SMN2 (0.70) | CDK5CDK5R1NPC1RAB9AKDM4E | |
| SCHEMBL8524322 | 0.69 | CDC25A (0.49) | CDK5CDK5R1NPC1RAB9AKDM4E | |
| SCHEMBL8525368 | 0.68 | SMN1; SMN2 (0.60) | CDK5CDK5R1NPC1RAB9AKDM4E | |
| SCHEMBL23657751 | 0.67 | CYP17A1 (0.73) | CDK5CDK5R1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |