Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SREBF2 | Q12772 | 8/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SREBF1 | P36956 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524612 | 0.82 | CYP19A1 (0.54) | CYP19A1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL8524544 | 0.78 | CYP19A1 (0.44) | CYP19A1MAPTSREBF2CDK5CDK5R1 | |
| SCHEMBL8525110 | 0.73 | CDK5 (0.42) | CYP19A1MAPTNPC1RAB9AMMP12 | |
| SCHEMBL8524764 | 0.72 | CYP19A1 (0.45) | CYP19A1MAPTNPC1RAB9AMMP12 | |
| SCHEMBL8525270 | 0.69 | SMN1; SMN2 (0.70) | CYP19A1MAPTNPC1RAB9AMMP12 | |
| SCHEMBL8525368 | 0.67 | SMN1; SMN2 (0.60) | CYP19A1MAPTNPC1RAB9AMMP12 | |
| SCHEMBL15682858 | 0.66 | AHR (0.54) | CYP19A1MAPTNPC1RAB9AMMP12 | |
| SCHEMBL2015591 | 0.66 | RARA (0.44) | — | |
| SCHEMBL8484612 | 0.66 | RAB9A (0.47) | CYP19A1MAPTNPC1RAB9AMMP12 | |
| SCHEMBL8524322 | 0.66 | CDC25A (0.49) | CYP19A1NPC1RAB9APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |