Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | AHR | P35869 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29069383 | 0.85 | MAPT (0.70) | MAPTPOLBHPGDHCAR3RAB9A | |
| SCHEMBL30767829 | 0.85 | MAPT (0.70) | MAPTPOLBHPGDHCAR3RAB9A | |
| SCHEMBL2876917 | 0.84 | HCAR3 (0.69) | MAPTPOLBHPGDHCAR3RAB9A | |
| SCHEMBL29751005 | 0.80 | HCAR3 (0.73) | MAPTPOLBHPGDHCAR3RAB9A | |
| SCHEMBL21409085 | 0.80 | HCAR3 (0.73) | MAPTPOLBHPGDHCAR3RAB9A | |
| SCHEMBL12369468 | 0.79 | HCAR3 (0.76) | MAPTPOLBHPGDHCAR3RAB9A | |
| SCHEMBL599138 | 0.79 | HCAR3 (1.00) | MAPTPOLBHPGDHCAR3RAB9A | |
| SCHEMBL25857631 | 0.78 | RAB9A (1.00) | MAPTPOLBHPGDHCAR3RAB9A | |
| SCHEMBL6125865 | 0.78 | RAB9A (0.83) | MAPTPOLBHPGDHCAR3RAB9A | |
| SCHEMBL241491 | 0.77 | HCAR3 (0.73) | MAPTPOLBHPGDHCAR3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932568-A | GASTROINTESTINAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-08-03 | — | — | US | disclosed |