Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 6/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GABRD | O14764 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8392019 | 0.85 | NPC1 (0.60) | KMT2ATSHRHPGDTP53ALDH1A1 | |
| SCHEMBL8524626 | 0.85 | ATM (0.54) | KMT2ATSHRHPGDTP53ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8393950 | 0.84 | NPC1 (0.58) | KMT2ATSHRHPGDTP53ALDH1A1 | |
| SCHEMBL24166525 | 0.84 | KMT2A (0.65) | KMT2ATSHRHPGDTP53ALDH1A1 | |
| SCHEMBL18478351 | 0.84 | HPGD (0.69) | KMT2ATSHRHPGDTP53ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8525129 | 0.83 | ATM (0.53) | KMT2ATSHRHPGDTP53ALDH1A1 | |
| SCHEMBL8524617 | 0.83 | ATM (0.53) | KMT2ATSHRHPGDTP53ALDH1A1 | |
| SCHEMBL16700120 | 0.82 | KMT2A (0.63) | KMT2ATSHRHPGDTP53ALDH1A1 | |
| SCHEMBL3455356 | 0.81 | HTT (0.66) | KMT2ATSHRHPGDTP53ALDH1A1 | |
| SCHEMBL8392821 | 0.81 | GAA (0.59) | KMT2AHPGDTP53ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885985-A | Guanidine derivatives useful in therapy | ASTRA AKTIEBOLAG (SE) | 1999-03-23 | — | — | US | claimed |