Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524702 | 0.83 | KMT2A (0.64) | ATMKMT2ATSHRALDH1A1HTT | |
| SCHEMBL8524626 | 0.83 | ATM (0.54) | ATMKMT2ATSHRALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL8525129 | 0.82 | ATM (0.53) | ATMKMT2ATSHRALDH1A1HTT | |
| SCHEMBL8392821 | 0.79 | GAA (0.59) | ATMKMT2AALDH1A1HTTTP53 | |
| Hydrochloric Acid SCHEMBL8396116 | 0.78 | GAA (0.58) | ATMKMT2AALDH1A1HTTTP53 | |
| SCHEMBL8392094 | 0.76 | ALDH1A1 (0.68) | KMT2AALDH1A1HPGDRAB9AMEN1 | |
| SCHEMBL8392632 | 0.76 | POLB (0.57) | KMT2AALDH1A1HTTRAB9ALMNA | |
| SCHEMBL4930738 | 0.75 | EPHX2 (0.47) | KMT2ATSHRALDH1A1MEN1NPSR1 | |
| SCHEMBL28284716 | 0.75 | MEN1 (0.51) | KMT2AALDH1A1HTTRAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL8397107 | 0.75 | POLB (0.56) | KMT2AALDH1A1HTTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885985-A | Guanidine derivatives useful in therapy | ASTRA AKTIEBOLAG (SE) | 1999-03-23 | — | — | US | claimed |
| US-5885985-A | Guanidine derivatives useful in therapy | ASTRA AKTIEBOLAG (SE) | 1999-03-23 | — | — | US | disclosed |