Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 4/20 | 0.39 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542406 | 0.77 | HTT (0.47) | MAPTHTTL3MBTL1KCNK9F2 | |
| SCHEMBL7453096 | 0.76 | LMNA (0.48) | MAPTPAX8KMT2ALMNAMEN1 | |
| SCHEMBL7380397 | 0.75 | CASR (0.47) | MAPTPAX8F7CASRHTT | |
| SCHEMBL19426798 | 0.73 | PLK4 (0.48) | KCNK9KMT2ALMNAKCNK3MEN1 | |
| SCHEMBL26049628 | 0.72 | NPSR1 (0.46) | HTTL3MBTL1KCNK9KMT2ALMNA | |
| SCHEMBL7856471 | 0.72 | TP53 (0.45) | PRMT5WDR77MAPTCASRHTT | |
| SCHEMBL6778195 | 0.72 | ITGB3 (0.43) | F7CASRF2KMT2AMEN1 | |
| SCHEMBL7379927 | 0.72 | KMT2A (0.45) | MAPTF7HTTF2KMT2A | |
| SCHEMBL7372871 | 0.72 | PLK4 (0.50) | KCNK9KMT2AKCNK3MEN1NPC1 | |
| SCHEMBL6366986 | 0.72 | PLA2G10 (0.47) | MAPTHTTL3MBTL1KCNK9PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889877-A1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | G.D. SEARLE & CO. (US) | 1999-01-13 | — | — | EP | claimed |
| WO-1997036862-A1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | claimed |