⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5493064 | 0.79 | — | — | |
| SCHEMBL727839 | 0.74 | — | — | |
| SCHEMBL826669 | 0.70 | — | — | |
| SCHEMBL66564 | 0.69 | — | — | |
| SCHEMBL32838 | 0.67 | — | — | |
| SCHEMBL15402187 | 0.67 | — | — | |
| SCHEMBL6598205 | 0.65 | — | — | |
| SCHEMBL4426696 | 0.65 | — | — | |
| SCHEMBL6114041 | 0.64 | — | — | |
| SCHEMBL5169518 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869650-A | POTENTIATE CYTOTOXICITY OF ANTICANCER DRUGS | FOX CHASE CANCER CENTER (US) | 1999-02-09 | — | — | US | disclosed |
| WO-1997048708-A1 | DENDROAMIDE COMPOUNDS AND THEIR USE IN CHEMOSENSITIZING MULTIDRUG RESISTANT CELLS | FOX CHASE CANCER CENTER (US) | 1997-12-24 | — | — | WO | disclosed |