Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NEK2 | P51955 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | CBX7 | O95931 | 1/20 | 0.36 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.36 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.36 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6361200 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MAPTEPHX2NEK2SMN1; SMN2 | |
| SCHEMBL1145012 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPTEPHX2L3MBTL1SMYD3 | |
| SCHEMBL5467106 | 0.77 | MAPT (0.52) | ALDH1A1MAPTEPHX2SMYD3KDM4E | |
| SCHEMBL6221019 | 0.76 | EPHX2 (0.44) | ALDH1A1MAPTEPHX2SMN1; SMN2USP2 | |
| SCHEMBL8524419 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPTNEK2SMN1; SMN2USP2 | |
| SCHEMBL1545660 | 0.75 | SIRT2 (0.58) | ALDH1A1MAPTNEK2SMN1; SMN2SMYD3 | |
| SCHEMBL18114133 | 0.75 | PDE3B (0.49) | ALDH1A1MAPTEPHX2NEK2SMN1; SMN2 | |
| SCHEMBL27076351 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MAPTEPHX2NEK2SMN1; SMN2 | |
| SCHEMBL1304506 | 0.75 | EPHX2 (0.59) | ALDH1A1MAPTEPHX2SMYD3GRIN2B | |
| SCHEMBL9768375 | 0.74 | BRD4 (0.56) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |