Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.43 |
| ▸ | MET | P08581 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | INSR | P06213 | 2/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450714 | 0.86 | HDAC3 (0.56) | ALDH1A1MAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL8524882 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL8525367 | 0.81 | SMN1; SMN2 (0.38) | ALDH1A1MAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL9184645 | 0.77 | CYP3A4 (0.59) | ALDH1A1CYP3A4CYP26A1CYP26B1RARA | |
| SCHEMBL6218261 | 0.76 | HDAC6 (0.54) | ALDH1A1MAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL8524985 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL1145012 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL5680486 | 0.76 | PGR (0.50) | ALDH1A1MAPTSMN1; SMN2USP2F2 | |
| SCHEMBL15304426 | 0.74 | CYP3A4 (0.50) | ALDH1A1MAPTMETCYP3A4INSR | |
| SCHEMBL11470235 | 0.74 | HDAC6 (0.54) | ALDH1A1MAPTHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |