Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525257 | 0.82 | SMN1; SMN2 (0.49) | NOTUML3MBTL1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL8525086 | 0.80 | RAB9A (0.60) | NOTUML3MBTL1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL8524775 | 0.80 | NPC1 (0.63) | NOTUML3MBTL1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL8524927 | 0.78 | NPC1 (0.50) | NOTUML3MBTL1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL8525315 | 0.78 | NPC1 (0.50) | ADORA1NOTUML3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL8525155 | 0.78 | L3MBTL1 (0.56) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL11281996 | 0.77 | NPC1 (0.50) | NOTUML3MBTL1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL8525304 | 0.77 | NPC1 (0.50) | NOTUML3MBTL1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL29496946 | 0.75 | MEN1 (0.56) | PDE4AL3MBTL1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL5797361 | 0.75 | MEN1 (0.56) | PDE4AL3MBTL1SMN1; SMN2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007352-A2 | METHOD FOR PROMOTING EXPRESSION OF LDL RECEPTOR GENE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-02-18 | — | — | WO | claimed |