Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2422286 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL8769688 | 0.84 | MAPT (0.41) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| Ether SCHEMBL4296253 | 0.78 | MAPT (0.41) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL10754824 | 0.77 | KDM4E (0.40) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL15951533 | 0.77 | KDM4E (0.40) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL174594 | 0.76 | ALDH1A1 (0.44) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL10719408 | 0.76 | CA2 (0.46) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL29006872 | 0.76 | ALDH1A1 (0.44) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL3267413 | 0.75 | MAPT (0.40) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL5755350 | 0.75 | POLB (0.41) | KDM4EALDH1A1HTR1AADRA2CADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602173-B1 | TOPICAL FIBRINOGEN COMPLEX | BAXTER INT (US) | 1999-05-26 | — | — | EP | claimed |