Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525087 | 0.83 | NPC1 (0.64) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL8524777 | 0.83 | NPC1 (0.68) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL11288499 | 0.83 | NPY5R (0.57) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL11137248 | 0.81 | NPC1 (0.53) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL11135408 | 0.81 | RAB9A (0.53) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL11135466 | 0.81 | NPC1 (0.53) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL8524931 | 0.81 | NPC1 (0.53) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL11140374 | 0.81 | NPC1 (0.53) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL8525318 | 0.81 | NPC1 (0.53) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL11131683 | 0.81 | NPC1 (0.53) | SMN1; SMN2NPC1RAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007352-A2 | METHOD FOR PROMOTING EXPRESSION OF LDL RECEPTOR GENE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-02-18 | — | — | WO | claimed |
| EP-0030038-B1 | 1,2,4-TRIAZINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-10-05 | — | — | EP | disclosed |
| US-4343801-A | FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-08-10 | — | — | US | disclosed |
| EP-0030038-A1 | 1,2,4-Triazine derivatives, process for their production and pharmaceutical composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-06-10 | — | — | EP | disclosed |