Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CBFB | Q13951 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | KRAS | P01116 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525087 | 0.89 | NPC1 (0.64) | NPC1RAB9AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL8524777 | 0.88 | NPC1 (0.68) | NPC1RAB9AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL11131683 | 0.86 | NPC1 (0.53) | NPC1RAB9AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL11140374 | 0.86 | NPC1 (0.53) | NPC1RAB9AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL11135466 | 0.86 | NPC1 (0.53) | NPC1RAB9AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL11135408 | 0.86 | RAB9A (0.53) | NPC1RAB9AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL11137248 | 0.86 | NPC1 (0.53) | NPC1RAB9AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL8524931 | 0.86 | NPC1 (0.53) | NPC1RAB9AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL8041610 | 0.83 | HTT (0.50) | NPC1RAB9AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL11132251 | 0.83 | L3MBTL1 (0.53) | NPC1RAB9AHTTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007352-A2 | METHOD FOR PROMOTING EXPRESSION OF LDL RECEPTOR GENE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-02-18 | — | — | WO | claimed |
| EP-0030038-B1 | 1,2,4-TRIAZINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-10-05 | — | — | EP | disclosed |
| US-4343801-A | FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-08-10 | — | — | US | disclosed |
| EP-0030038-A1 | 1,2,4-Triazine derivatives, process for their production and pharmaceutical composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-06-10 | — | — | EP | disclosed |