Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | JAK1 | P23458 | 2/20 | 0.37 |
| ▸ | JAK3 | P52333 | 2/20 | 0.37 |
| ▸ | FPR3 | P25089 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24322481 | 0.83 | PKM (0.43) | PKMITGB3ITGA2BHPGD | |
| SCHEMBL27256861 | 0.82 | CYP1A2 (0.44) | PKMITGB3ITGA2BALDH1A1 | |
| SCHEMBL17282576 | 0.82 | PREP (0.50) | MMP1MMP2MMP8JAK2JAK1 | |
| SCHEMBL17275494 | 0.82 | HPGD (0.41) | PKMMMP1MMP2MMP8ITGB3 | |
| SCHEMBL4239694 | 0.82 | HPGD (0.41) | PKMMMP1MMP2MMP8ITGB3 | |
| SCHEMBL13337051 | 0.81 | DPP4 (0.41) | DPP7MMP1MMP2MMP8JAK2 | |
| SCHEMBL17991731 | 0.80 | PREP (0.49) | MMP1MMP2MMP8JAK2JAK1 | |
| SCHEMBL5552024 | 0.80 | MMP1 (0.41) | MMP1MMP2MMP8JAK2JAK1 | |
| SCHEMBL13337035 | 0.78 | DPP4 (0.39) | DPP7MMP1MMP2MMP8JAK2 | |
| SCHEMBL13337040 | 0.78 | DPP4 (0.39) | DPP7MMP1MMP2MMP8JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927161-A1 | SUBSTITUTED CYCLIC AMINE METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998008815-A1 | SUBSTITUTED CYCLIC AMINE METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |