Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | EIF4E | P06730 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8480857 | 0.77 | KDM4E (0.50) | CYP19A1KDM4ESMN1; SMN2RAB9ALMNA | |
| SCHEMBL8525368 | 0.74 | SMN1; SMN2 (0.60) | CYP19A1KDM4ESMN1; SMN2RAB9ALMNA | |
| SCHEMBL8525270 | 0.74 | SMN1; SMN2 (0.70) | CYP19A1KDM4ESMN1; SMN2RAB9ALMNA | |
| SCHEMBL8480061 | 0.72 | PDE3B (0.68) | CYP19A1KDM4ESMN1; SMN2RAB9ALMNA | |
| SCHEMBL16090231 | 0.71 | KDR (0.57) | SMN1; SMN2RAB9ALMNANPC1KMT2A | |
| SCHEMBL5902233 | 0.71 | MAPT (0.66) | KDM4EARCDK5CDK5R1KMT2A | |
| SCHEMBL8524006 | 0.69 | RAB9A (0.44) | CYP19A1KDM4ESMN1; SMN2RAB9ALMNA | |
| SCHEMBL16090213 | 0.69 | TLK2 (0.54) | — | |
| SCHEMBL16090235 | 0.69 | TLK2 (0.54) | SMN1; SMN2RAB9ALMNANPC1CDK5 | |
| SCHEMBL8484612 | 0.69 | RAB9A (0.47) | CYP19A1KDM4ESMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |