Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | TPMT | P51580 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6306274 | 0.81 | TPMT (0.39) | AKR1C2AKR1C1TPMTTSHRALDH1A1 | |
| SCHEMBL7950440 | 0.81 | GRM2 (0.36) | CYP3A4HPGDSRCHCAR1MEN1 | |
| SCHEMBL28668982 | 0.78 | AKR1C4 (0.43) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT | |
| SCHEMBL17431766 | 0.75 | TPMT (0.48) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT | |
| SCHEMBL15019326 | 0.73 | TPMT (0.46) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT | |
| SCHEMBL28011467 | 0.73 | TPMT (0.46) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT | |
| SCHEMBL15018999 | 0.73 | TPMT (0.46) | AKR1C4AKR1C3AKR1C2AKR1C1TPMT | |
| SCHEMBL9365706 | 0.73 | TSHR (0.50) | TSHRALDH1A1HSD17B10CASP1SMN1; SMN2 | |
| SCHEMBL6838455 | 0.72 | ALDH1A1 (0.42) | AKR1C3AKR1C2TPMTTSHRALDH1A1 | |
| SCHEMBL31603827 | 0.70 | MEN1 (0.44) | SRCMEN1KMT2ACYP2D6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985883-A | FUNGICIDAL ACTIVITY AGAINST RICE BLAST DISEASE | AMERICAN CYANAMID COMPANY (US) | 1999-11-16 | — | — | US | disclosed |