Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838455 | 0.90 | ALDH1A1 (0.42) | TPMTALDH1A1GPR35HTTTSHR | |
| SCHEMBL5481803 | 0.83 | ALDH1A1 (0.47) | TPMTALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL8525339 | 0.81 | AKR1C4 (0.45) | TPMTALDH1A1GPR35TSHRKMT2A | |
| SCHEMBL6806673 | 0.79 | KDM4E (0.42) | TPMTALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL21269842 | 0.77 | KDM4E (0.41) | TPMTALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL21268965 | 0.77 | KDM4E (0.41) | TPMTALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL21269629 | 0.77 | KDM4E (0.41) | TPMTALDH1A1LMNAKDM4EL3MBTL1 | |
| SCHEMBL7950440 | 0.77 | GRM2 (0.36) | KMT2AMEN1SRCHCAR1HPGD | |
| SCHEMBL7486568 | 0.77 | MAPK1 (0.43) | ALDH1A1GPR35HTTTSHRMAPT | |
| SCHEMBL31458693 | 0.76 | MYC (0.40) | TPMTALDH1A1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050164885-A1 | Alkyl dihalogenated phenyl-substituted ketoenols useful as pesticides and herbicides | BAYER AG (DE) | 2005-07-28 | — | — | US | disclosed |
| US-6858741-B2 | Alkyl-dihalogenated phenyl-substituted ketoenols useful as pesticides and herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2005-02-22 | — | — | US | disclosed |
| US-20030199572-A1 | Alkyl-dihalogenophenyl-substituted ketoenols | LIEB FOLKER (DE) | 2003-10-23 | — | — | US | disclosed |
| EP-0825982-B1 | ALKYL DIHALOGENATED PHENYL-SUBSTITUTED KETOENOLS USEFUL AS PESTICIDES AND HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2002-11-27 | — | — | EP | disclosed |
| US-6380246-B1 | FOR COMBATING PESTS AND WEEDS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-04-30 | — | — | US | disclosed |
| US-6316486-B1 | FOR COMBATING PESTS AND WEED | BAYER AKTIENGESELLSCHAFT (DE) | 2001-11-13 | — | — | US | disclosed |
| EP-0825982-A1 | ALKYL DIHALOGENATED PHENYL-SUBSTITUTED KETOENOLS USEFUL AS PESTICIDES AND HERBICIDES | BAYER AG (DE) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996035664-A1 | ALKYL DIHALOGENATED PHENYL-SUBSTITUTED KETOENOLS USEFUL AS PESTICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050164885-A1 | Alkyl dihalogenated phenyl-substituted ketoenols useful as pesticides and herbicides | DDT, CYP8B1, PAOX | TPMT 4141/4885ALDH1A1 938/4885GPR35 2401/4885 |
| US-20030199572-A1 | Alkyl-dihalogenophenyl-substituted ketoenols | CYP2E1, CYP8B1, CYP24A1 | TPMT 4350/4885ALDH1A1 497/4885GPR35 2147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.