Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 19/20 | 0.48 |
| ▸ | HTR2A | P28223 | 18/20 | 0.48 |
| ▸ | HTR2B | P41595 | 17/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972018 | 0.83 | HTR2C (0.58) | HTR2CHTR2AHTR2BCYP2C9CYP1A2 | |
| SCHEMBL7981950 | 0.82 | HTR2C (0.59) | HTR2CHTR2AHTR2BCYP2C9NOTUM | |
| SCHEMBL2478158 | 0.78 | PDK1 (0.34) | HTR2CHTR2AHTR2BCYP2C9HTR6 | |
| SCHEMBL26600961 | 0.77 | DRD2 (0.48) | HTR2CHTR2AHTR2B | |
| SCHEMBL26601042 | 0.75 | HTR2A (0.43) | HTR2CHTR2AHTR2BCYP2C9HTR6 | |
| SCHEMBL7373998 | 0.73 | NOTUM (0.59) | HTR2CHTR2AHTR2BNOTUM | |
| SCHEMBL7479611 | 0.73 | NOTUM (0.59) | HTR2CHTR2AHTR2BNOTUM | |
| SCHEMBL2474940 | 0.73 | AVPR2 (0.35) | HTR2C | |
| SCHEMBL2530222 | 0.73 | CNR2 (0.62) | HTR2CHTR2AHTR2BNOTUM | |
| SCHEMBL30681440 | 0.73 | NOTUM (0.76) | HTR2CHTR2AHTR2BCYP2C9NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999043650-A2 | PROCESS(ES) FOR THE PREPARATION OF 6-TRIFLUOROMETHYL-INDOLINE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1999-09-02 | — | — | WO | disclosed |