Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CBFB | Q13951 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041610 | 0.86 | HTT (0.50) | ALDH1A1HTTCBFBHSP90AA1KMT2A | |
| SCHEMBL11133762 | 0.84 | NPC1 (0.49) | ALDH1A1HTTCBFBHSP90AA1KMT2A | |
| SCHEMBL8524777 | 0.82 | NPC1 (0.68) | ALDH1A1HTTHSP90AA1KMT2ANPSR1 | |
| SCHEMBL11136903 | 0.81 | NPC1 (0.49) | ALDH1A1HTTCBFBTDP1L3MBTL1 | |
| SCHEMBL8525087 | 0.79 | NPC1 (0.64) | ALDH1A1HTTHSP90AA1KMT2ANPSR1 | |
| SCHEMBL8525305 | 0.79 | NPC1 (0.49) | ALDH1A1HTTKMT2ANPSR1TDP1 | |
| SCHEMBL11137884 | 0.78 | NPC1 (0.51) | ALDH1A1HTTKMT2ANPSR1L3MBTL1 | |
| SCHEMBL8525516 | 0.78 | PIM1 (0.49) | ALDH1A1HTTCBFBHSP90AA1KMT2A | |
| SCHEMBL8525259 | 0.78 | SMN1; SMN2 (0.48) | ALDH1A1HTTHSP90AA1KMT2ANPSR1 | |
| SCHEMBL11135466 | 0.77 | NPC1 (0.53) | ALDH1A1HTTCBFBHSP90AA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007352-A2 | METHOD FOR PROMOTING EXPRESSION OF LDL RECEPTOR GENE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-02-18 | — | — | WO | claimed |
| EP-0030038-B1 | 1,2,4-TRIAZINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-10-05 | — | — | EP | disclosed |
| US-4343801-A | FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-08-10 | — | — | US | disclosed |
| EP-0030038-A1 | 1,2,4-Triazine derivatives, process for their production and pharmaceutical composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-06-10 | — | — | EP | disclosed |