Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CBFB | Q13951 | 2/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041608 | 0.87 | L3MBTL1 (0.48) | TGFBR1NPC1RAB9ASMN1; SMN2CBFB | |
| SCHEMBL8524775 | 0.82 | NPC1 (0.63) | PIM1TGFBR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8525086 | 0.80 | RAB9A (0.60) | PIM1NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL8525257 | 0.79 | SMN1; SMN2 (0.49) | NPC1RAB9ASMN1; SMN2MAPK9L3MBTL1 | |
| SCHEMBL8525304 | 0.79 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2MAPK13MAPK12 | |
| SCHEMBL8525519 | 0.78 | ALDH1A1 (0.47) | PIM1TGFBR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8524927 | 0.75 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL8525315 | 0.75 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2CBFBL3MBTL1 | |
| SCHEMBL29979429 | 0.75 | TGFBR1 (0.60) | TGFBR1NPC1RAB9ASMN1; SMN2CBFB | |
| SCHEMBL4025464 | 0.75 | TGFBR1 (0.60) | TGFBR1NPC1RAB9ASMN1; SMN2CBFB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007352-A2 | METHOD FOR PROMOTING EXPRESSION OF LDL RECEPTOR GENE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-02-18 | — | — | WO | claimed |