SCHEMBL852559

SCHEMBL852559

[c]1ccc2[nH]c3cc[c]cc3c2c1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
HSD17B10 Q99714 2/20 0.39
GPR3 P46089 1/20 0.39
KDM4E B2RXH2 2/20 0.33
AHR P35869 1/20 0.33
LMNA P02545 1/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
ATM Q13315 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
TSHR P16473 1/20 0.30
GFER P55789 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25035 0.89 ALDH1A1 (0.61) ALDH1A1HSD17B10GPR3KDM4EAHR
SCHEMBL5999667 0.85 ALDH1A1 (0.35) ALDH1A1HSD17B10GPR3KDM4EAHR
SCHEMBL7796203 0.82 CHUK (0.49) ALDH1A1KDM4ELMNAGAAHPGD
SCHEMBL10580049 0.80 PARP1 (0.47) ALDH1A1KDM4ELMNAHPGDSMN1; SMN2
SCHEMBL496951 0.80 CHUK (0.59) ALDH1A1KDM4EHPGDSMN1; SMN2
SCHEMBL166213 0.78 ALDH1A1 (0.39) ALDH1A1HSD17B10GPR3AHR
SCHEMBL3227577 0.77 ALDH1A1 (0.32) ALDH1A1HSD17B10GPR3
SCHEMBL314742 0.77 AHR (0.52) ALDH1A1HSD17B10KDM4EAHRLMNA
SCHEMBL16031128 0.75 PARP1 (0.53) ALDH1A1HSD17B10GPR3KDM4ELMNA
SCHEMBL25590 0.74 ALDH1A1 (0.61) ALDH1A1HSD17B10GPR3KDM4EAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3519490-B1 MOISTURE CURABLE POLYOLEFIN COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-03-20 EP claimed
EP-3535312-B1 SEMI-CRYSTALLINE POLYOLEFIN-BASED ADDITIVE MASTERBATCH COMPOSITION DOW GLOBAL TECHNOLOGIES LLC (US) 2024-02-21 EP claimed
CN-109790300-B Semi-crystalline polyolefin-based additive masterbatch composition 陶氏环球技术有限责任公司 2022-09-13 CN claimed
CN-109890878-B Semicrystalline polyolefin additive masterbatch composition 陶氏环球技术有限责任公司 2022-07-08 CN claimed
CN-109890877-B Additive masterbatch composition based on semicrystalline polyolefins 陶氏环球技术有限责任公司 2022-06-28 CN claimed
US-11370891-B2 Semi-crystalline polyolefin-based additive masterbatch composition DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-28 US claimed
US-11186711-B2 Semi-crystalline polyolefin-based additive masterbatch composition DOW GLOBAL TECHNOLOGIES LLC (US) 2021-11-30 US claimed
EP-3294727-B1 ORGANIC LIGHT-EMITTING DIODE COMPRISING DIFFERENT MATRIX COMPOUNDS IN THE FIRST AND SECOND ELECTRON TRANSPORT LAYER NOVALED GMBH (DE) 2021-08-04 EP claimed
US-11081652-B2 Organic light-emitting diode comprising different matrix compounds in the first and second electron transport layer NOVALED GMBH (DE) 2021-08-03 US claimed
EP-3535313-B1 SEMI-CRYSTALLINE POLYOLEFIN-BASED ADDITIVE MASTERBATCH COMPOSITION DOW GLOBAL TECHNOLOGIES LLC (US) 2021-06-30 EP claimed
WO-2006096399-A2 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-14 WO claimed
CN-1829725-A aromatic monomer and conjugated polymer-metal complex SUMITOMO CHEMICAL CO (JP) 2006-09-06 CN claimed
WO-2005049546-A1 HALOGENATED BISDIARYLAMINOPOLYCYLIC AROMATIC COMPOUNDS AND POLYMERS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-06-02 WO claimed
US-20050106324-A1 Method of preparing an insoluble polymer film on a substrate from a soluble polymer containing labile solubilizing groups DOW GLOBAL TECHNOLOGIES LLC 2005-05-19 US claimed
WO-2005036666-A2 METHOD OF PREPARING AN INSOLUBLE POLYMER FILM ON A SUBSTRATE FROM A SOLUBLE POLYMER CONTAINING LABILE SOLUBILIZING GROUPS DOW GLOBAL TECHNOLOGIES INC. (US) 2005-04-21 WO claimed
WO-2005016945-A1 AROMATIC MONOMER-AND CONJUGATED POLYMER-METAL COMPLEXES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-02-24 WO claimed
US-20050031900-A1 Aromatic monomer-and conjugated polymer-metal complexes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-02-10 US claimed
WO-2005010081-A1 AROMATIC MONOMER-AND CONJUGATED POLYMER-METAL COMPLEXES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-02-03 WO claimed
US-20050014023-A1 Aromatic monomer- and conjugated polymer-metal complexes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-01-20 US claimed
US-4371467-A HYDROLYSIS OF BASIC SALT DAINIPPON INK AND CHEMICALS INC. (JP) 1983-02-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11081652-B2 Organic light-emitting diode comprising different matrix compounds in the first and second electron transport layer CYBA, CLTB, MAP1LC3B ALDH1A1 122/4885HSD17B10 442/4885GPR3 3811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.