Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | F9 | P00740 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526165 | 0.86 | LRRK2 (0.38) | MAPTHSP90AA1HTTSMN1; SMN2MAPK10 | |
| SCHEMBL8175262 | 0.81 | CYP1A2 (0.48) | MAPTHSP90AA1HTTSMN1; SMN2MAPK10 | |
| SCHEMBL8180740 | 0.77 | MAPK10 (0.43) | MAPTHSP90AA1HTTSMN1; SMN2MAPK10 | |
| SCHEMBL8525055 | 0.75 | MAPK10 (0.35) | MAPTHSP90AA1HTTSMN1; SMN2MAPK10 | |
| SCHEMBL8524608 | 0.75 | MAPT (0.35) | MAPTHSP90AA1HTTSMN1; SMN2MAPK10 | |
| SCHEMBL8524143 | 0.74 | LRRK2 (0.38) | MAPTHSP90AA1HTTSMN1; SMN2MAPK10 | |
| SCHEMBL8183594 | 0.74 | MAPK10 (0.37) | MAPTHSP90AA1HTTSMN1; SMN2MAPK10 | |
| SCHEMBL8181128 | 0.74 | HSD11B1 (0.40) | MAPTHSP90AA1HTTSMN1; SMN2MAPK10 | |
| SCHEMBL8177966 | 0.74 | MAPT (0.41) | MAPTHSP90AA1HTTSMN1; SMN2MAPK10 | |
| SCHEMBL8525951 | 0.74 | MAPT (0.41) | MAPTHSP90AA1HTTSMN1; SMN2MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |