SCHEMBL8525810

SCHEMBL8525810

CC(O)C(NC(=O)C(N)Cc1ccccc1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MME P08473 3/20 0.67
CTSC P53634 2/20 0.59
ALPI P09923 1/20 0.56
PKM P14618 1/20 0.56
PTGS1 P23219 1/20 0.56
XIAP P98170 1/20 0.56
SLC7A5 Q01650 1/20 0.56
OPRM1 P35372 3/20 0.54
OPRD1 P41143 3/20 0.54
LTA4H P09960 1/20 0.51
ECE1 P42892 1/20 0.49
CTRB1 P17538 2/20 0.49
SLC15A1 P46059 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31174322 1.00 MME (0.67) MMECTSCALPIPKMPTGS1
SCHEMBL8525812 1.00 MME (0.67) MMECTSCALPIPKMPTGS1
SCHEMBL29543743 0.95 MME (0.61) MMECTSCALPIPKMPTGS1
SCHEMBL30735658 0.93 OPRD1 (0.62) MMECTSCALPIPKMPTGS1
SCHEMBL31215109 0.93 OPRD1 (0.62) MMECTSCALPIPKMPTGS1
SCHEMBL1711844 0.92 MME (0.58) MMECTSCALPIPKMPTGS1
SCHEMBL29377179 0.92 MME (0.57) MMECTSCALPIPKMPTGS1
SCHEMBL31215083 0.91 OPRD1 (0.60) MMECTSCOPRM1OPRD1
SCHEMBL29351955 0.91 CTSD (0.57) MMECTSCALPIPKMPTGS1
SCHEMBL30974432 0.90 MME (0.56) MMECTSCOPRM1OPRD1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250155441-A1 HIGH AFFINITY ANTIBODIES SPECIFICALLY BINDING TO a-1,6-CORE-FUCOSYLATED ALPHA-FETOPROTEIN ROCHE DIAGNOSTICS OPERATIONS, INC. 2025-05-15 US disclosed
EP-4526341-A1 HIGH AFFINITY ANTIBODIES SPECIFICALLY BINDING TO ALPHA-1,6-CORE-FUCOSYLATED ALPHA-FETOPROTEIN F. Hoffmann-La Roche AG (CH) 2025-03-26 EP disclosed
CN-119213025-A High affinity antibodies that specifically bind to alpha-1, 6-core-fucosylated alpha-fetoprotein 豪夫迈·罗氏有限公司 2024-12-27 CN disclosed
WO-2023222543-A1 High Affinity Antibodies Specifically Binding to α-1,6-Core-Fucosylated Alpha-Fetoprotein F. HOFFMANN-LA ROCHE AG (CH) 2023-11-23 WO disclosed
CN-114224908-A Application of cordyceps militaris polysaccharide in preparation of product for regulating intestinal flora and metabolite disorder caused by high-fat diet 暨南大学 2022-03-25 CN disclosed
EP-0885899-A1 Method for obtaining peptide fragments by use of fluorinated organic acids SEIKO INSTRUMENTS INC. (JP) 1998-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250155441-A1 HIGH AFFINITY ANTIBODIES SPECIFICALLY BINDING TO a-1,6-CORE-FUCOSYLATED ALPHA-FETOPROTEIN FUCA1, FUCA2, FUT4 MME 1897/4885CTSC 1995/4885ALPI 922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.