Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.59 |
| ▸ | PADI4 | Q9UM07 | 6/20 | 0.51 |
| ▸ | PADI2 | Q9Y2J8 | 4/20 | 0.51 |
| ▸ | PDE4A | P27815 | 2/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.51 |
| ▸ | PADI6 | Q6TGC4 | 2/20 | 0.51 |
| ▸ | FURIN | P09958 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | MC3R | P41968 | 1/20 | 0.44 |
| ▸ | MC1R | Q01726 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526187 | 0.93 | MCHR1 (0.60) | MCHR1PADI4PADI2PDE4APDE4B | |
| SCHEMBL7750688 | 0.92 | MCHR1 (0.59) | MCHR1PADI4PADI2PDE4APDE4B | |
| SCHEMBL7751919 | 0.85 | MCHR1 (0.53) | MCHR1PADI4PADI2PDE4APDE4B | |
| SCHEMBL16181256 | 0.80 | NPY1R (0.58) | FURINNPY1R | |
| SCHEMBL7039837 | 0.80 | NPY1R (0.60) | MCHR1NPY1R | |
| SCHEMBL4650743 | 0.79 | NPY1R (0.61) | NPY1R | |
| SCHEMBL16181288 | 0.79 | NPY1R (0.56) | FURINNPY1R | |
| SCHEMBL16181277 | 0.78 | NPY1R (0.54) | FURINNPY1R | |
| SCHEMBL13691806 | 0.78 | ITGB3 (0.47) | MCHR1PADI4PADI2PDE4APDE4B | |
| SCHEMBL8515668 | 0.78 | HDAC1 (0.45) | MCHR1PADI4PADI2PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |