Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.53 |
| ▸ | PADI4 | Q9UM07 | 8/20 | 0.50 |
| ▸ | PADI2 | Q9Y2J8 | 5/20 | 0.50 |
| ▸ | PDE4A | P27815 | 2/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.50 |
| ▸ | PADI6 | Q6TGC4 | 2/20 | 0.50 |
| ▸ | FURIN | P09958 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
| ▸ | MC1R | Q01726 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1388417 | 0.89 | PADI6 (0.44) | MCHR1PADI4PADI2PDE4APDE4B | |
| SCHEMBL8526187 | 0.87 | MCHR1 (0.60) | MCHR1PADI4PADI2PDE4APDE4B | |
| SCHEMBL7750688 | 0.86 | MCHR1 (0.59) | MCHR1PADI4PADI2PDE4APDE4B | |
| SCHEMBL9286645 | 0.86 | MCHR1 (0.50) | MCHR1PADI4PADI2PDE4APDE4B | |
| SCHEMBL8114285 | 0.86 | MCHR1 (0.50) | MCHR1PADI4PADI2PDE4APDE4B | |
| SCHEMBL8525943 | 0.85 | MCHR1 (0.59) | MCHR1PADI4PADI2PDE4APDE4B | |
| SCHEMBL4650700 | 0.81 | NPY1R (0.55) | MCHR1 | |
| SCHEMBL1388294 | 0.81 | TACR1 (0.46) | PADI6 | |
| SCHEMBL8515668 | 0.76 | HDAC1 (0.45) | MCHR1PADI4PADI2PDE4APDE4B | |
| SCHEMBL7549487 | 0.76 | NPY4R (0.46) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | claimed |
| US-6313128-B1 | CAN BE USED AS LYPOLYSIS/LYPOGENESIS REGULATORS IN THE SKIN WITHOUT, INTERFERRING WITH THE SKIN'S NATURAL FUNCTIONS; FOR THERAPY OF SABORRHEA AND ACNE | SANOFI-SYNTHELABO (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |