Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.44 |
| ▸ | OXTR | P30559 | 2/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8505556 | 0.94 | OXTR (0.48) | PTGES2OXTRAVPR1AHSD11B1ACLY | |
| Benzenesulfonamide SCHEMBL8524570 | 0.85 | CA12 (0.48) | PTGES2CA12CA1CA2CA9 | |
| Benzenesulfonamide SCHEMBL8525288 | 0.85 | CA12 (0.48) | CA12CA1CA2CA9PTGS2 | |
| Benzenesulfonamide SCHEMBL8525761 | 0.85 | CA1 (0.48) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL8503384 | 0.81 | CYP2C9 (0.54) | CYP2C9ALDH1A1LMNA | |
| Benzenesulfonamide SCHEMBL8526038 | 0.81 | PTGES2 (0.48) | PTGES2CA12CA1CA2CA9 | |
| Benzenesulfonamide SCHEMBL8525643 | 0.80 | CA1 (0.46) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL8506074 | 0.78 | CYP2C9 (0.52) | MAPTCYP2C9ALDH1A1LMNA | |
| SCHEMBL8504924 | 0.78 | CYP2C9 (0.52) | CA12CA1CA2CA9MAPT | |
| SCHEMBL8505905 | 0.78 | CYP2C9 (0.51) | CYP2C9ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946507-A1 | SUBSTITUTED PYRROLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998025896-A1 | SUBSTITUTED PYRROLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-06-18 | — | — | WO | disclosed |