Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 15/20 | 0.59 |
| ▸ | CTSL | P07711 | 4/20 | 0.58 |
| ▸ | CTSS | P25774 | 4/20 | 0.58 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | FCER2 | P06734 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 2/20 | 0.44 |
| ▸ | NPY4R | P50391 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528337 | 0.92 | CTSB (0.57) | CTSBCTSLCTSSKLKB1KLK1 | |
| SCHEMBL8119544 | 0.91 | CTSB (0.60) | CTSBCTSLCTSSKLKB1KLK1 | |
| SCHEMBL8119060 | 0.88 | CTSB (0.59) | CTSBCTSLCTSSKLKB1KLK1 | |
| SCHEMBL7039825 | 0.87 | CTSB (0.56) | CTSBCTSLCTSSKLKB1KLK1 | |
| SCHEMBL8118532 | 0.84 | CTSB (0.56) | CTSBCTSLCTSSKLKB1KLK1 | |
| SCHEMBL7040956 | 0.83 | CTSB (0.61) | CTSBCTSLCTSS | |
| SCHEMBL8586104 | 0.83 | CTSB (0.61) | CTSBCTSLCTSS | |
| SCHEMBL7040960 | 0.83 | CTSB (0.61) | CTSBCTSLCTSS | |
| SCHEMBL8125308 | 0.81 | CTSB (0.59) | CTSBCTSLCTSS | |
| SCHEMBL8120139 | 0.81 | CTSB (0.63) | CTSBCTSLCTSSMMP1FCER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |