Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 14/20 | 0.61 |
| ▸ | CTSL | P07711 | 3/20 | 0.60 |
| ▸ | CTSS | P25774 | 3/20 | 0.60 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 2/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8586104 | 1.00 | CTSB (0.61) | CTSBCTSLCTSSGPR34MME | |
| SCHEMBL7040956 | 1.00 | CTSB (0.61) | CTSBCTSLCTSSGPR34MME | |
| SCHEMBL8125308 | 0.91 | CTSB (0.59) | CTSBCTSLCTSS | |
| SCHEMBL8111430 | 0.86 | CTSB (0.63) | CTSBCTSLCTSSMME | |
| SCHEMBL8526387 | 0.86 | CTSB (0.63) | CTSBCTSLCTSSMME | |
| SCHEMBL8586882 | 0.85 | CTSB (0.56) | CTSBCTSLCTSS | |
| SCHEMBL8121321 | 0.84 | GPR34 (0.52) | CTSBGPR34MMEFOLH1 | |
| SCHEMBL8119544 | 0.84 | CTSB (0.60) | CTSBCTSLCTSS | |
| SCHEMBL8526178 | 0.83 | CTSB (0.59) | CTSBCTSLCTSS | |
| SCHEMBL12247346 | 0.83 | FOLH1 (0.52) | CTSBGPR34MMEFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | disclosed |
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |