Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 4/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 2/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8585458 | 0.82 | ENPP1 (0.53) | MEN1KMT2AKDRENPP1 | |
| SCHEMBL4375637 | 0.77 | SRC (0.44) | SRCKDRIP6K1DHFRENPP1 | |
| SCHEMBL8525484 | 0.76 | KDM1A (0.46) | SRCKDR | |
| SCHEMBL1012303 | 0.73 | SRC (0.52) | SRCKDRPDPK1 | |
| SCHEMBL1780281 | 0.73 | SRC (0.52) | SRCKDRPDPK1 | |
| SCHEMBL4374144 | 0.72 | SRC (0.47) | SRCKDRIP6K1EHMT2DHFR | |
| SCHEMBL8917 | 0.72 | SRC (0.63) | SRCIP6K1PDPK1 | |
| SCHEMBL7451899 | 0.72 | SRC (0.41) | SRCKDRIP6K1ENPP1 | |
| SCHEMBL664912 | 0.72 | SRC (0.51) | SRCKDRIP6K1DHFRENPP1 | |
| SCHEMBL4376398 | 0.72 | SRC (0.51) | SRCKDRIP6K1DHFRENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912557-A1 | OXINDOLE DERIVATIVES | ZENECA LIMITED (GB) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997042187-A1 | OXINDOLE DERIVATIVES | ZENECA LIMITED (GB) | 1997-11-13 | — | — | WO | disclosed |