Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 6/20 | 0.40 |
| ▸ | KDR | P35968 | 9/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526248 | 0.82 | MEN1 (0.41) | ENPP1MEN1KMT2AKDR | |
| SCHEMBL16760479 | 0.82 | ENPP1 (0.64) | ENPP1EGFRKDR | |
| SCHEMBL8525239 | 0.77 | TNF (0.44) | MEN1KMT2A | |
| SCHEMBL3951030 | 0.77 | ENPP1 (0.73) | ENPP1EGFRKDR | |
| SCHEMBL4375574 | 0.77 | ENPP1 (0.62) | ENPP1EGFRKDR | |
| SCHEMBL8526204 | 0.75 | EGFR (0.53) | EGFRKDR | |
| SCHEMBL3947513 | 0.73 | ENPP1 (0.71) | ENPP1EGFRKDR | |
| SCHEMBL1011386 | 0.73 | ENPP1 (0.70) | ENPP1KDR | |
| SCHEMBL4373124 | 0.72 | ENPP1 (0.68) | ENPP1KDR | |
| SCHEMBL1012226 | 0.72 | ENPP1 (0.68) | ENPP1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912557-A1 | OXINDOLE DERIVATIVES | ZENECA LIMITED (GB) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997042187-A1 | OXINDOLE DERIVATIVES | ZENECA LIMITED (GB) | 1997-11-13 | — | — | WO | disclosed |