Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27397292 | 0.82 | HSD17B10 (0.47) | MEN1CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL3535148 | 0.82 | BRD4 (0.32) | MEN1CYP2D6CYP2C9CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL27583753 | 0.77 | EPHX1 (0.47) | CYP2D6EPHX1DPP4 | |
| SCHEMBL17140609 | 0.77 | LMNA (0.38) | EPHX1 | |
| SCHEMBL16935655 | 0.77 | — | — | |
| SCHEMBL5144744 | 0.77 | — | — | |
| SCHEMBL544671 | 0.76 | EPHX1 (0.50) | CYP2D6EPHX1DPP4 | |
| SCHEMBL2332933 | 0.76 | EPHX1 (0.50) | CYP2D6EPHX1DPP4 | |
| SCHEMBL1218849 | 0.76 | EPHX1 (0.50) | CYP2D6EPHX1DPP4 | |
| SCHEMBL10822383 | 0.76 | EPHX1 (0.53) | CYP2C9EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1326440-A | Piperdine CCR-3 receptor antagonists | HOFFMANN LA ROCHE (CH) | 2001-12-12 | — | — | CN | claimed |
| CN-1326440-A | Piperdine CCR-3 receptor antagonists | HOFFMANN LA ROCHE (CH) | 2001-12-12 | — | — | CN | disclosed |
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |