SCHEMBL2332933

SCHEMBL2332933

NC(=O)[C@H](N)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.50
CYP2D6 P10635 2/20 0.48
SRC P12931 1/20 0.48
DPP4 P27487 2/20 0.48
F2 P00734 1/20 0.48
LMNA P02545 2/20 0.46
MAPK1 P28482 1/20 0.46
CYP1A2 P05177 1/20 0.45
PKM P14618 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
ALOX5 P09917 1/20 0.45
CTSD P07339 1/20 0.45
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1218849 1.00 EPHX1 (0.50) EPHX1CYP2D6SRCDPP4F2
SCHEMBL544671 1.00 EPHX1 (0.50) EPHX1CYP2D6SRCDPP4F2
Hydrochloric Acid SCHEMBL1137431 0.98 EPHX1 (0.48) EPHX1CYP2D6SRCDPP4F2
Hydrochloric Acid SCHEMBL28645850 0.98 EPHX1 (0.48) EPHX1CYP2D6SRCDPP4F2
Hydrochloric Acid SCHEMBL1137429 0.98 EPHX1 (0.48) EPHX1CYP2D6SRCDPP4F2
Methane SCHEMBL6241814 0.98 EPHX1 (0.48) EPHX1CYP2D6SRCDPP4F2
Hydrochloric Acid SCHEMBL1137441 0.98 EPHX1 (0.48) EPHX1CYP2D6SRCDPP4F2
Hydrochloric Acid SCHEMBL27583753 0.95 EPHX1 (0.47) EPHX1CYP2D6SRCDPP4F2
Acetic Acid SCHEMBL27430362 0.93 ALOX5 (0.46) EPHX1CYP2D6SRCDPP4F2
SCHEMBL7193261 0.87 PTGS2 (0.52) DPP4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9458463-B2 Method for treatment of diabetes by a small molecule inhibitor for GRK5 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2016-10-04 US claimed
WO-2015022437-A1 INDOLINONE DERIVATIVES AS GRK5 MODULATORS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2015-02-19 WO claimed
WO-1990008126-A1 RESOLUTION PROCESS Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) 1990-07-26 WO claimed
EP-4308168-B1 METHODS FOR PREPARING CYCLOOCTENES AND CONJUGATES THEREOF TAGWORKS PHARMACEUTICALS B V (NL) 2026-05-20 EP disclosed
US-20260103455-A1 ULK3 INHIBITORS AND USES THEREOF H LEE MOFFITT CANCER CT & RES (US) 2026-04-16 US disclosed
CN-121627535-A Deracemization method of phenylglycine amide 天津大学 2026-03-10 CN disclosed
US-12384757-B2 Methods of synthesizing substituted pyridinone-pyridinyl compounds ACLARIS THERAPEUTICS, INC. (US) 2025-08-12 US disclosed
US-12344589-B2 Method for producing a 1,5-benzothiazepin compound ELOBIX AB (SE) 2025-07-01 US disclosed
US-20250135005-A1 PROCESSES FOR PREPARING FUNCTIONALIZED CYCLOOCTENES TAMBO INC (US) 2025-05-01 US disclosed
CN-119823023-A Process for preparing functionalized cyclooctenes 坦博公司 2025-04-15 CN disclosed
CN-113473975-B Process for preparing functionalized cyclooctenes 坦博公司 2025-01-21 CN disclosed
CN-1046523-C Process for making antimicrobial quinolonyl lactams PROCTER & GAMBLE PHARMA (US) 1999-11-17 CN disclosed
US-5801242-A Process for making quinolonyl lactam antimicrobials and novel intermediate compounds THE PROCTER & GAMBLE COMPANY (US) 1998-09-01 US disclosed
US-5703231-A Process for making antimicrobial compounds THE PROCTER & GAMBLE COMPANY (US) 1997-12-30 US disclosed
CN-1159809-A Process for making quinolonyl lactam antimicrobials and novel intermediate compounds PROCTER & GAMBLE (US) 1997-09-17 CN disclosed
CN-1158120-A Process for the preparation of antimicrobial compounds PROCTER & GAMBLE (US) 1997-08-27 CN disclosed
CN-1075146-A The method for preparing antimicrobial quinolonyl lactams PROCTER & GAMBLE PHARMA (US) 1993-08-11 CN disclosed
US-5053509-A Microbiocides; AIDS LABORATOIRE ROGER BELLON (FR) 1991-10-01 US disclosed
EP-0411074-A1 RESOLUTION PROCESS CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1991-02-06 EP disclosed
WO-1990008126-A1 RESOLUTION PROCESS Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) 1990-07-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12384757-B2 Methods of synthesizing substituted pyridinone-pyridinyl compounds PIR, PUM1, ZRANB2 EPHX1 2634/4885CYP2D6 719/4885SRC 3285/4885
US-12344589-B2 Method for producing a 1,5-benzothiazepin compound CYP3A5, KCNJ5, KCNK5 EPHX1 1827/4885CYP2D6 193/4885SRC 4765/4885
US-20250135005-A1 PROCESSES FOR PREPARING FUNCTIONALIZED CYCLOOCTENES PPOX, SCO2, CYCS EPHX1 1595/4885CYP2D6 139/4885SRC 976/4885
US-20260103455-A1 ULK3 INHIBITORS AND USES THEREOF ULK3, ULK1, ULK2 EPHX1 4802/4885CYP2D6 4475/4885SRC 1082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.