Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL10897308 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TSHRHDAC8CYP2A6HTR2A | |
| Styrene SCHEMBL7947690 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TSHRHDAC8CYP2A6HTR2A | |
| SCHEMBL10618368 | 0.79 | ALDH1A1 (0.41) | ALDH1A1TSHRHDAC8CYP2A6HTR2A | |
| Styrene SCHEMBL10628448 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TSHRHDAC8CYP2A6HTR2A | |
| Styrene SCHEMBL6378780 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TSHRHDAC8CYP2A6HTR2A | |
| Styrene SCHEMBL17927763 | 0.77 | ALDH1A1 (0.61) | ALDH1A1TSHRHDAC8CYP2A6HTR2A | |
| Styrene SCHEMBL21485240 | 0.77 | ALDH1A1 (0.88) | ALDH1A1TSHRHDAC8CYP2A6TAAR1 | |
| Styrene SCHEMBL369036 | 0.76 | ALDH1A1 (1.00) | ALDH1A1TSHRHDAC8CYP2A6SMN1; SMN2 | |
| Styrene SCHEMBL140 | 0.76 | — | — | |
| Styrene SCHEMBL6258482 | 0.76 | ALDH1A1 (1.00) | ALDH1A1TSHRHDAC8CYP2A6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920436-A1 | DELIVERY AND SCAVENGING AGENTS FOR COMBINATORIAL SYNTHESIS | SYMYX TECHNOLOGIES (US) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998056796-A1 | DELIVERY AND SCAVENGING AGENTS FOR COMBINATORIAL SYNTHESIS | SYMYX TECHNOLOGIES (US) | 1998-12-17 | — | — | WO | disclosed |