Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8179403 | 0.77 | MEN1 (0.37) | ALDH1A1RECQLHPGDTSHR | |
| SCHEMBL28893915 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HPGD | |
| SCHEMBL2376555 | 0.74 | FOLH1 (0.45) | FOLH1TSHR | |
| SCHEMBL743998 | 0.74 | CYP2D6 (0.48) | ALDH1A1RECQLHPGD | |
| SCHEMBL8421401 | 0.71 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL2354778 | 0.70 | EPHX1 (0.40) | ALDH1A1TSHR | |
| SCHEMBL29010635 | 0.68 | TSHR (0.43) | ALDH1A1RECQLHPGDTSHR | |
| SCHEMBL7745307 | 0.67 | ALDH1A1 (0.48) | ALDH1A1RECQLHPGDTSHR | |
| SCHEMBL6369101 | 0.67 | ALDH1A1 (0.48) | ALDH1A1RECQLHPGDTSHR | |
| SCHEMBL6470541 | 0.67 | ALDH1A1 (0.48) | ALDH1A1RECQLHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |