Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | SCN4A | P35499 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17287844 | 0.86 | GBA1 (0.52) | GBA1SCN4ADPP4F2 | |
| SCHEMBL2486785 | 0.83 | GBA1 (0.49) | GBA1SCN4ADPP4F2 | |
| SCHEMBL9298053 | 0.83 | GBA1 (0.49) | GBA1SCN4ADPP4F2 | |
| SCHEMBL4204978 | 0.81 | CA1 (0.50) | GBA1CA1CA2CA5ACA9 | |
| SCHEMBL28956494 | 0.81 | GBA1 (0.56) | GBA1CA1CA2CA5ACA9 | |
| SCHEMBL12497701 | 0.81 | GBA1 (0.47) | GBA1CA1CA2CA5ACA9 | |
| SCHEMBL390880 | 0.78 | GABBR2 (0.49) | CA1CA2CA5ACA9SCN4A | |
| SCHEMBL6432062 | 0.77 | DPP4 (0.50) | GBA1CA1CA2CA5ACA9 | |
| Hydrochloric Acid SCHEMBL29143639 | 0.77 | GBA1 (0.47) | GBA1SCN4APTGES2 | |
| SCHEMBL17258982 | 0.76 | PTGES2 (0.57) | GBA1CA1CA2CA5ACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3186232-A1 | P38 MAP KINASE INHIBITING INDANYL UREA COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2017-07-05 | — | — | EP | claimed |
| WO-2016030852-A1 | P38 MAP KINASE INHIBITING INDANYL UREA COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2016-03-03 | — | — | WO | claimed |
| EP-2683704-B1 | BRANCHED OXATHIAZINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS MEDICINE AND DRUG CONTAINING SAID DERIVATIVES AND USE THEREOF | SANOFI SA (FR) | 2014-12-17 | — | — | EP | disclosed |
| EP-2683704-B1 | BRANCHED OXATHIAZINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS MEDICINE AND DRUG CONTAINING SAID DERIVATIVES AND USE THEREOF | SANOFI SA (FR) | 2014-12-17 | — | — | EP | disclosed |
| US-8828995-B2 | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof | SANOFI (FR) | 2014-09-09 | — | — | US | disclosed |
| US-8828995-B2 | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof | SANOFI (FR) | 2014-09-09 | — | — | US | disclosed |
| EP-2683704-A1 | BRANCHED OXATHIAZINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS MEDICINE AND DRUG CONTAINING SAID DERIVATIVES AND USE THEREOF | SANOFI (FR) | 2014-01-15 | — | — | EP | disclosed |
| WO-2012120053-A1 | BRANCHED OXATHIAZINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS MEDICINE AND DRUG CONTAINING SAID DERIVATIVES AND USE THEREOF | SANOFI (FR) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012120053-A1 | BRANCHED OXATHIAZINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS MEDICINE AND DRUG CONTAINING SAID DERIVATIVES AND USE THEREOF | SANOFI (FR) | 2012-09-13 | — | — | WO | disclosed |
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |