Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17086715 | 0.83 | TAAR1 (0.50) | PTGES2TAAR1AOC3GRIA4TRPA1 | |
| SCHEMBL6718127 | 0.83 | TAAR1 (0.50) | PTGES2TAAR1AOC3GRIA4TRPA1 | |
| SCHEMBL17086665 | 0.83 | TAAR1 (0.50) | PTGES2TAAR1AOC3GRIA4TRPA1 | |
| SCHEMBL31452189 | 0.81 | TAAR1 (0.48) | PTGES2TAAR1AOC3GRIA4TRPA1 | |
| SCHEMBL7161040 | 0.81 | TAAR1 (0.48) | PTGES2TAAR1AOC3GRIA4TRPA1 | |
| SCHEMBL5217546 | 0.81 | TAAR1 (0.48) | PTGES2TAAR1AOC3GRIA4TRPA1 | |
| SCHEMBL1275322 | 0.81 | GRIA4 (0.56) | PTGES2GRIA4CA1CA2CA5A | |
| SCHEMBL5217923 | 0.81 | TAAR1 (0.48) | PTGES2TAAR1AOC3GRIA4TRPA1 | |
| SCHEMBL5217555 | 0.81 | TAAR1 (0.48) | PTGES2TAAR1AOC3GRIA4TRPA1 | |
| SCHEMBL4204978 | 0.79 | CA1 (0.50) | PTGES2TAAR1CA1CA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105764987-B | Powder slush moulding composition | 和仁化学株式会社 | 2018-09-14 | — | — | CN | claimed |
| CN-105764987-A | Powder slush molding composition | 和仁化学株式会社 | 2016-07-13 | — | — | CN | claimed |
| CN-103380239-B | Controlled degradation fibers | 3M INNOVATIVE PROPERTIES CO | 2015-05-13 | — | — | CN | claimed |
| US-20240336590-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | ANNAPURNA BIO, INC. | 2024-10-10 | — | — | US | disclosed |
| US-11724997-B2 | Compounds and compositions for treating conditions associated with APJ receptor activity | ANNAPURNA BIO, INC. (US) | 2023-08-15 | — | — | US | disclosed |
| US-11724997-B2 | Compounds and compositions for treating conditions associated with APJ receptor activity | ANNAPURNA BIO, INC. (US) | 2023-08-15 | — | — | US | disclosed |
| US-11724997-B2 | Compounds and compositions for treating conditions associated with APJ receptor activity | ANNAPURNA BIO, INC. (US) | 2023-08-15 | — | — | US | disclosed |
| US-20210053936-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | ANNAPURNA BIO, INC. | 2021-02-25 | — | — | US | disclosed |
| US-20210053936-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | ANNAPURNA BIO, INC. | 2021-02-25 | — | — | US | disclosed |
| CN-112055713-A | Compounds and compositions for treating diseases associated with APJ receptor activity | 安娜普尔纳生物股份有限公司 | 2020-12-08 | — | — | CN | disclosed |
| CN-108976178-A | A kind of preparation method of chiral sulfonamide class organic compound | 云南民族大学 | 2018-12-11 | — | — | CN | disclosed |
| CN-105764987-B | Powder slush moulding composition | 和仁化学株式会社 | 2018-09-14 | — | — | CN | disclosed |
| US-10022376-B2 | Pyrazolopyridines and pyrazolopyrimidines | PFIZER INC. (US) | 2018-07-17 | — | — | US | disclosed |
| US-20170071946-A1 | PYRAZOLOPYRIDINES AND PYRAZOLOPYRIMIDINES | PFIZER INC. (US) | 2017-03-16 | — | — | US | disclosed |
| US-9518052-B2 | Pyrazolopyridines and pyrazolopyrimidines | PFIZER INC. (US) | 2016-12-13 | — | — | US | disclosed |
| CN-105764987-A | Powder slush molding composition | 和仁化学株式会社 | 2016-07-13 | — | — | CN | disclosed |
| CN-105431511-A | Bio-Based Dispersants | ETHOX CHEMICALS LLC | 2016-03-23 | — | — | CN | disclosed |
| US-20150329542-A1 | PYRAZOLOPYRIDINES AND PYRAZOLOPYRIMIDINES | PFIZER INC. | 2015-11-19 | — | — | US | disclosed |
| CN-102958540-B | Containing the combination of 2,3-glyoxalidine also [1, the 2-C] quinazoline replaced | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-09-02 | — | — | CN | disclosed |
| CN-103380239-B | Controlled degradation fibers | 3M INNOVATIVE PROPERTIES CO | 2015-05-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11724997-B2 | Compounds and compositions for treating conditions associated with APJ receptor activity | APLNR, AGTR1, AGTR2 | PTGES2 1172/4885TAAR1 1160/4885AOC3 4082/4885 |
| US-20210053936-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | APLNR, AGTR1, AGTR2 | PTGES2 1172/4885TAAR1 1160/4885AOC3 4082/4885 |
| US-10022376-B2 | Pyrazolopyridines and pyrazolopyrimidines | CBR3, HRH4, REN | PTGES2 4284/4885TAAR1 633/4885AOC3 285/4885 |
| US-20150329542-A1 | PYRAZOLOPYRIDINES AND PYRAZOLOPYRIMIDINES | HRH2, HRH4, HRH1 | PTGES2 3254/4885TAAR1 1347/4885AOC3 180/4885 |
| US-20240336590-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | APLNR, AGTR1, AGTR2 | PTGES2 1172/4885TAAR1 1160/4885AOC3 4082/4885 |
| US-20170071946-A1 | PYRAZOLOPYRIDINES AND PYRAZOLOPYRIMIDINES | HRH2, HRH4, HRH1 | PTGES2 3254/4885TAAR1 1347/4885AOC3 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.