SCHEMBL8526510

SCHEMBL8526510

CC(O)COC1CCCCC1C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.36
HTT P42858 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9187798 1.00 MAPK1 (0.36) MAPK1HTTMEN1KMT2AL3MBTL1
SCHEMBL9188490 1.00 MAPK1 (0.36) MAPK1HTTMEN1KMT2AL3MBTL1
SCHEMBL118256 0.83 MEN1 (0.36) HTTMEN1KMT2AL3MBTL1
SCHEMBL21402635 0.83 MEN1 (0.36) HTTMEN1KMT2AL3MBTL1
SCHEMBL9191326 0.83 MEN1 (0.36) HTTMEN1KMT2AL3MBTL1
SCHEMBL3912889 0.83 MEN1 (0.36) HTTMEN1KMT2AL3MBTL1
SCHEMBL19924608 0.83 MEN1 (0.36) HTTMEN1KMT2AL3MBTL1
SCHEMBL1826286 0.83 MEN1 (0.31) HTTMEN1KMT2A
SCHEMBL14646344 0.78 MAPK1 (0.36) MAPK1HTTMEN1KMT2A
SCHEMBL9186431 0.78 MEN1 (0.33) HTTMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4217937-A None JP disclosed
EP-2799417-B1 METHOD OF PRODUCING 1-(2-t-BUTYL CYCLOHEXYLOXY)-2-ALKANOL KAO CORP (JP) 2017-06-07 EP disclosed
CN-104024198-B The manufacture method of 1-(2-tert-butylcyclohexoxy)-2-alkanol 花王株式会社 2016-08-17 CN disclosed
US-8927777-B2 Method of producing 1-(2-t-butyl cyclohexyloxy)-2-alkanol KAO CORPORATION (JP) 2015-01-06 US disclosed
US-20140350306-A1 METHOD OF PRODUCING 1-(2-t-BUTYL CYCLOHEXYLOXY)-2-ALKANOL KAO CORPORATION (JP) 2014-11-27 US disclosed
EP-2799417-A1 METHOD OF PRODUCING 1-(2-t-BUTYL CYCLOHEXYLOXY)-2-ALKANOL Kao Corporation (JP) 2014-11-05 EP disclosed
CN-104024198-A Method of producing 1-(2-t-butyl cyclohexyloxy)-2-alkanol KAO CORP 2014-09-03 CN disclosed
EP-0616994-B1 Process for producing ether alcohols by hydrogenolysis of cyclic ketal KAO CORP (JP) 1998-12-30 EP disclosed
CN-1034277-C alpha-(alkylcyclohexyloxy)-beta-alkanols and perfume compositions containing same KAO CORP (JP) 1997-03-19 CN disclosed
EP-0467290-B1 Alpha-(alkylcyclohexyloxy)-beta-alkanols and perfume compositions containing the same KAO CORP (JP) 1995-10-11 EP disclosed
US-5446208-A Process for producing ether alcohols by hydrogenolysis of cyclic ketal KAO CORPORATION (JP) 1995-08-29 US disclosed
EP-0616994-A2 Process for producing ether alcohols by hydrogenolysis of cyclic ketal KAO CORPORATION (JP) 1994-09-28 EP disclosed
US-5194423-A ALPHA-(ALKYLCYCLOHEXYLOXY)-BETA-ALKANOLS AND PERFUME COMPOSITIONS CONTAINING THE SAME KAO CORPORATION (JP) 1993-03-16 US disclosed
JP-H04217937-A ALPHA-(ALKYLCYCLOHEXYLOXY)-BETA-ALKANOLS AND PERFUME COMPOSITION CONTAINING THE SAME ALKANOLS KAO CORP 1992-08-07 JP disclosed
EP-0467290-A2 Alpha-(alkylcyclohexyloxy)-beta-alkanols and perfume compositions containing the same Kao Corporation (JP) 1992-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140350306-A1 METHOD OF PRODUCING 1-(2-t-BUTYL CYCLOHEXYLOXY)-2-ALKANOL TRPA1, TPSD1, TPSB2 MAPK1 1829/4885HTT 2808/4885MEN1 791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.