SCHEMBL8526532

SCHEMBL8526532

COc1ccc(N)cc1.COc1ccc(N)cc1OC

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.67
MAPK1 P28482 2/20 0.67
ALDH1A1 P00352 5/20 0.64
CYP3A4 P08684 2/20 0.64
CA12 O43570 1/20 0.61
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
CA7 P43166 1/20 0.61
CA9 Q16790 1/20 0.61
CA14 Q9ULX7 1/20 0.61
CYP19A1 P11511 4/20 0.56
MAPT P10636 3/20 0.56
GAA P10253 3/20 0.56
KDM4E B2RXH2 2/20 0.56
NR4A1 P22736 2/20 0.53
APP P05067 2/20 0.53
MEN1 O00255 1/20 0.53
THRB P10828 1/20 0.53
KMT2A Q03164 1/20 0.53
TUBB4A P04350 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2438047 0.89 KDM4E (0.67) MAPK1ALDH1A1CYP3A4CA12CA1
SCHEMBL77823 0.89 KDM4E (0.67) MAPK1ALDH1A1CYP3A4CA12CA1
SCHEMBL29377777 0.89 KDM4E (0.67) MAPK1ALDH1A1CYP3A4CA12CA1
SCHEMBL11401708 0.88 MAPK1 (0.56) TDP1MAPK1ALDH1A1CYP3A4CA12
Hydrochloric Acid SCHEMBL2479850 0.87 MAPT (0.70) TDP1MAPK1ALDH1A1CYP3A4CA12
Ammonia Solution, Strong SCHEMBL5361377 0.87 KDM4E (0.64) MAPK1ALDH1A1CYP3A4CA12CA1
Methane SCHEMBL27340305 0.87 KDM4E (0.64) MAPK1ALDH1A1CYP3A4CA12CA1
SCHEMBL19692591 0.86 ALDH1A1 (0.75) TDP1MAPK1ALDH1A1CYP3A4CA12
SCHEMBL31457261 0.86 MAPT (0.55) TDP1MAPK1ALDH1A1CYP3A4CA12
Hydroxyamine SCHEMBL4369811 0.85 KDM4E (0.62) MAPK1ALDH1A1CYP3A4CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0479445-B1 Hydroxyl functionalized polyetheramines as barrier packaging for oxygen-sensitive materials DOW CHEMICAL CO (US) 1998-03-11 EP disclosed