Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530604 | 0.90 | HIF1A (0.50) | HIF1ASCN3AKCNH2CD274 | |
| SCHEMBL8528118 | 0.90 | HIF1A (0.46) | HIF1AKCNH2 | |
| SCHEMBL8529479 | 0.84 | MAPK1 (0.47) | HIF1AKCNH2KMT2A | |
| SCHEMBL8529279 | 0.83 | HIF1A (0.45) | HIF1ASCN3AKCNH2 | |
| SCHEMBL8371601 | 0.83 | HIF1A (0.55) | HIF1AFFAR4PARP14PARP10MEN1 | |
| SCHEMBL8371602 | 0.83 | HIF1A (0.55) | HIF1AFFAR4PARP14PARP10MEN1 | |
| SCHEMBL8399074 | 0.83 | HIF1A (0.55) | HIF1AFFAR4PARP14PARP10MEN1 | |
| SCHEMBL8399234 | 0.81 | HIF1A (0.64) | HIF1ASLC6A2SLC6A4SLC6A3PARP14 | |
| SCHEMBL8399228 | 0.81 | HIF1A (0.64) | HIF1ASLC6A2SLC6A4SLC6A3PARP14 | |
| SCHEMBL8369603 | 0.79 | HIF1A (0.57) | HIF1APARP14PARP10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739140-A | AGRICULTURAL FUNGICIDES | MONSANTO COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| WO-1997016413-A9 | ARYL ACRYLICS FOR USE AS FUNGICIDE | — | 1997-08-14 | — | — | WO | disclosed |