Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529479 | 0.95 | MAPK1 (0.47) | HIF1AMAPK1MAPK14KCNH2HAO1 | |
| SCHEMBL8530604 | 0.90 | HIF1A (0.50) | HIF1AKCNH2KDM1AMAOAMAOB | |
| SCHEMBL8526539 | 0.90 | HIF1A (0.46) | HIF1AKCNH2 | |
| SCHEMBL8536325 | 0.88 | HIF1A (0.42) | HIF1AMAPK1MAPK14KCNH2HAO1 | |
| SCHEMBL8529279 | 0.88 | HIF1A (0.45) | HIF1AKCNH2MAOB | |
| SCHEMBL8529014 | 0.86 | MAPK1 (0.38) | HIF1AMAPK1MAPK14KCNH2HAO1 | |
| SCHEMBL8527006 | 0.84 | HIF1A (0.46) | HIF1AKCNH2 | |
| SCHEMBL8527151 | 0.84 | HIF1A (0.44) | HIF1AKCNH2 | |
| SCHEMBL8539263 | 0.84 | HIF1A (0.44) | HIF1AKCNH2 | |
| SCHEMBL7462516 | 0.83 | MAPK1 (0.46) | MAPK1MAPK14KCNH2HAO1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877730-A1 | ARYL ACRYLICS FOR USE AS FUNGICIDE | MONSANTO COMPANY (US) | 1998-11-18 | — | — | EP | disclosed |
| US-5739140-A | AGRICULTURAL FUNGICIDES | MONSANTO COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| WO-1997016413-A9 | ARYL ACRYLICS FOR USE AS FUNGICIDE | — | 1997-08-14 | — | — | WO | disclosed |
| WO-1997016413-A1 | ARYL ACRYLICS FOR USE AS FUNGICIDE | MONSANTO COMPANY (US) | 1997-05-09 | — | — | WO | disclosed |