SCHEMBL8526548

SCHEMBL8526548

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nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
ENPEP Q07075 7/20 0.45
MME P08473 3/20 0.41
ACE P12821 1/20 0.41
CPA1 P15085 1/20 0.41
ACE2 Q9BYF1 1/20 0.41
PDCD1LG2 Q9BQ51 1/20 0.41
CD274 Q9NZQ7 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CA2 P00918 4/20 0.38
CA1 P00915 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8526546 1.00 ALDH1A1 (0.46) ALDH1A1ENPEPMMEACECPA1
SCHEMBL31174309 1.00 ALDH1A1 (0.46) ALDH1A1ENPEPMMEACECPA1
SCHEMBL29352016 0.95 ALDH1A1 (0.46) ALDH1A1ENPEP
SCHEMBL30272494 0.92 ALDH1A1 (0.50) ALDH1A1ENPEPL3MBTL1CA2CA1
SCHEMBL2933768 0.89 ALDH1A1 (0.58) ALDH1A1ENPEPMMEACECPA1
SCHEMBL2933766 0.89 ALDH1A1 (0.58) ALDH1A1ENPEPMMEACECPA1
SCHEMBL31025662 0.89 ALDH1A1 (0.58) ALDH1A1ENPEPMMEACECPA1
SCHEMBL7441174 0.89 ALDH1A1 (0.58) ALDH1A1ENPEPMMEACECPA1
SCHEMBL30818044 0.89 ALDH1A1 (0.46) ALDH1A1ENPEP
SCHEMBL29641579 0.88 ALDH1A1 (0.47) ALDH1A1ENPEPMMEACECPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4650362-A1 NEUROPROTECTIVE PSD-95 POLYPEPTIDE INHIBITOR AND USE THEREOF Beijing Tuo Jie Biopharmaceutical Co. Ltd. (CN) 2025-11-19 EP claimed
US-12329799-B2 Peptidyl inhibitors of calcineurin-NFAT interaction OHIO STATE INNOVATION FOUNDATION (US) 2025-06-17 US claimed
CN-120044159-A Polygonatum sibiricum medicinal material species identification method based on polygonatum sibiricum characteristic compound and application 河北北方学院 2025-05-27 CN claimed
CN-119409797-A Tide robust peptide synthesis method 中肽生化有限公司 2025-02-11 CN claimed
WO-2024149230-A1 NEUROPROTECTIVE PSD-95 POLYPEPTIDE INHIBITOR AND USE THEREOF 北京拓界生物医药科技有限公司 2024-07-18 WO claimed
US-20240033318-A1 PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION OHIO STATE INNOVATION FOUNDATION 2024-02-01 US claimed
CN-111393508-B Preparation method of atosiban 上海苏豪逸明制药有限公司 2023-05-12 CN claimed
US-11576946-B2 Peptidyl inhibitors of calcineurin-NFAT interaction OHIO STATE INNOVATION FOUNDATION (US) 2023-02-14 US claimed
US-20220289846-A1 ANTIBODIES TO HUMAN PROGRAMMED DEATH RECEPTOR PD-1 ZYDUS LIFESCIENCES LIMITED (IN) 2022-09-15 US claimed
EP-3997126-A1 ANTIBODIES TO HUMAN PROGRAMMED DEATH RECEPTOR PD-1 Cadila Healthcare Limited (IN) 2022-05-18 EP claimed
CN-106456633-A Sugar metabolism improving agent 三得利控股株式会社 2017-02-22 CN claimed
CN-122011162-A Chemical synthesis method of N-terminal domain of TIMP2 protein 华南理工大学 2026-05-12 CN disclosed
EP-4684030-A2 METHOD OF DEPROTECTING AT LEAST ONE D-AMINO ACID AND/OR D-AMINO ACID DERIVATIVE PROTECTED FUNCTIONAL GROUP Martin-Luther-Universität Halle-Wittenberg (DE) 2026-01-28 EP disclosed
US-12516121-B2 Antibodies to human programmed death receptor PD-1 ZYDUS LIFESCIENCES LIMITED (IN) 2026-01-06 US disclosed
EP-3481849-B1 CHIMERIC DENGUE/ZIKA VIRUSES AS LIVE-ATTENUATED ZIKA VIRUS VACCINES US HEALTH (US) 2025-12-10 EP disclosed
WO-2020027689-A1 NOVEL USES OF A COMBINATION OF JUNIPER BERRY EXTRACT AND CHARCOAL ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "СПЛАТ ГЛОБАЛ" 2020-02-06 WO disclosed
US-20180314790-A1 System, Method and Apparatus for Determining the Effect of Genetic Variants METABOLON, INC. 2018-11-01 US disclosed
US-20170276669-A1 PRECISE ESTIMATION OF GLOMERULAR FILTRATION RATE FROM MULTIPLE BIOMARKERS NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2017-09-28 US disclosed
CN-106456633-A Sugar metabolism improving agent 三得利控股株式会社 2017-02-22 CN disclosed
EP-0885899-A1 Method for obtaining peptide fragments by use of fluorinated organic acids SEIKO INSTRUMENTS INC. (JP) 1998-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12329799-B2 Peptidyl inhibitors of calcineurin-NFAT interaction CHP1, NFATC1, PPP3R1 ALDH1A1 4851/4885ENPEP 1199/4885MME 1756/4885
US-20240033318-A1 PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION CHP1, NFATC1, PPP3R1 ALDH1A1 4851/4885ENPEP 1199/4885MME 1756/4885
US-11576946-B2 Peptidyl inhibitors of calcineurin-NFAT interaction CHP1, NFATC1, PPP3R1 ALDH1A1 4851/4885ENPEP 1199/4885MME 1756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.