Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 12/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | RARA | P10276 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | BID | P55957 | 3/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.48 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10391891 | 1.00 | RARB (0.57) | RARBMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL9394701 | 0.92 | RARB (0.61) | RARBMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL8526681 | 0.92 | RARB (0.61) | RARBMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL10438718 | 0.87 | ALOX5 (0.60) | MEN1MAPTKMT2AALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL8746734 | 0.86 | RARB (0.63) | RARBMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL10441217 | 0.84 | ALOX5 (0.57) | MEN1MAPTKMT2AALDH1A1TP53 | |
| SCHEMBL11056289 | 0.84 | ALOX5 (0.57) | MEN1MAPTKMT2AALDH1A1TP53 | |
| SCHEMBL10441000 | 0.84 | ALOX5 (0.57) | MEN1MAPTKMT2AALDH1A1TP53 | |
| SCHEMBL9507976 | 0.84 | RARB (0.70) | RARBMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL6884342 | 0.84 | SRD5A2 (0.53) | ALDH1A1PTPN11TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891358-A | ELECTROCLINIC DEVICE COMPRISING TWO SPACED CELL WALLS EACH BEARING ELECTRODE STRUCTURES AND TREATED ON AT LEAST ONE FACING SURFACE WITH AN ALIGNMENT LAYER, A LAYER OF A SMECTIC LIQUID CRYSTAL MATERIAL ENCLOSED BETWEEN THE CELL WALLS | SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITIAN & NORTHERN IRELAND OF DEFENCE EVALUATION & RESEARCH AGENCY (GB) | 1999-04-06 | — | — | US | disclosed |