Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.53 |
| ▸ | RXRA | P19793 | 2/20 | 0.51 |
| ▸ | RXRB | P28702 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6884735 | 0.90 | RXRA (0.51) | SRD5A2RXRARXRBHSD17B10HSD17B1 | |
| SCHEMBL9652658 | 0.88 | SRD5A2 (0.57) | SRD5A2RXRARXRBBCL2ALDH1A1 | |
| SCHEMBL11012461 | 0.86 | JAK1 (0.50) | HSD17B10HSD17B1ESR2JAK1JAK2 | |
| SCHEMBL10391891 | 0.84 | RARB (0.57) | TYRALDH1A1PTPN11 | |
| SCHEMBL8526683 | 0.84 | RARB (0.57) | TYRALDH1A1PTPN11 | |
| SCHEMBL25126172 | 0.84 | RXRA (0.59) | SRD5A2RXRARXRBHSD17B10BCL2 | |
| SCHEMBL3809402 | 0.84 | HSD17B1 (0.51) | HSD17B10HSD17B1ESR2JAK1JAK2 | |
| SCHEMBL1292805 | 0.82 | ALOX5 (0.59) | HSD17B10CA12CA9ESR2JAK1 | |
| SCHEMBL9751648 | 0.82 | BCL2 (0.58) | SRD5A2RXRARXRBBCL2ALDH1A1 | |
| SCHEMBL3885574 | 0.81 | SRD5A2 (0.54) | SRD5A2RXRARXRBHSD17B10HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004003561-A9 | PEPTIDE ROD AMPHIPHILES AND SELF-ASSEMBLY OF SAME | UNIV NORTHWESTERN (US) | 2004-08-12 | — | — | WO | disclosed |
| WO-2004003561-A1 | PEPTIDE ROD AMPHIPHILES AND SELF-ASSEMBLY OF SAME | NORTHWESTERN UNIVERSITY (US) | 2004-01-08 | — | — | WO | disclosed |
| US-5965763-A | Biphenyl compounds | HOECHST MARION ROUSSEL (FR) | 1999-10-12 | — | — | US | disclosed |
| US-5827887-A | 5-ALPHA REDUCTASE INHIBITORS | ROUSSEL UCLAF (FR) | 1998-10-27 | — | — | US | disclosed |