Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.88 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.62 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PNMT | P11086 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylamine SCHEMBL23581072 | 0.97 | LOXL2 (0.82) | LOXL2TAAR1CYP2A6HTR2ASMN1; SMN2 | |
| Benzylamine SCHEMBL9006462 | 0.94 | LOXL2 (0.88) | LOXL2TAAR1CYP2A6HTR2ASMN1; SMN2 | |
| Benzylamine SCHEMBL5481672 | 0.94 | LOXL2 (1.00) | LOXL2TAAR1CYP2A6HTR2ASMN1; SMN2 | |
| Benzylamine SCHEMBL1331207 | 0.94 | — | — | |
| Benzylamine SCHEMBL373 | 0.94 | — | — | |
| SCHEMBL19242392 | 0.94 | LOXL2 (1.00) | LOXL2TAAR1CYP2A6HTR2ASMN1; SMN2 | |
| Benzylamine SCHEMBL10707644 | 0.94 | LOXL2 (1.00) | LOXL2TAAR1CYP2A6HTR2ASMN1; SMN2 | |
| Benzylamine SCHEMBL6991195 | 0.91 | LOXL2 (0.82) | LOXL2TAAR1CYP2A6HTR2ASMN1; SMN2 | |
| Benzylamine SCHEMBL28934699 | 0.91 | LOXL2 (0.82) | LOXL2TAAR1CYP2A6HTR2ASMN1; SMN2 | |
| Benzylamine SCHEMBL9055495 | 0.91 | LOXL2 (0.82) | LOXL2TAAR1CYP2A6HTR2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105307657-A | Heteroaryl compounds and uses thereof | CELGENE AVILOMICS RES INC | 2016-02-03 | — | — | CN | disclosed |
| CN-102702737-B | Preparation method and application of supramolecular complex nanoparticles | CHINESE ACAD TECH INST PHYSICS | 2014-07-23 | — | — | CN | disclosed |
| CN-102702737-A | Preparation method and application of supramolecular complex nanoparticles | CHINESE ACAD TECH INST PHYSICS | 2012-10-03 | — | — | CN | disclosed |
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |