SCHEMBL8526863

SCHEMBL8526863

O=S(=O)(c1ccc(O)cc1)c1ccc(O)c(S(=O)(=O)c2ccccc2)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.77
POLB P06746 3/20 0.77
GFER P55789 1/20 0.77
ALDH1A1 P00352 2/20 0.55
PKM P14618 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.51
HTR6 P50406 1/20 0.48
TDP1 Q9NUW8 2/20 0.47
ALPL P05186 1/20 0.47
ALPI P09923 1/20 0.47
ALPG P10696 1/20 0.47
DNMT1 P26358 1/20 0.47
MCL1 Q07820 1/20 0.47
MAPT P10636 2/20 0.46
ATM Q13315 2/20 0.46
ERAP1 Q9NZ08 2/20 0.46
PTGS1 P23219 1/20 0.44
CA2 P00918 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6534882 0.95 GAA (0.73) GAAPOLBGFERALDH1A1PKM
SCHEMBL660467 0.95 GAA (0.73) GAAPOLBGFERALDH1A1PKM
SCHEMBL7126365 0.93 POLB (0.66) GAAPOLBGFERALDH1A1PKM
SCHEMBL2862398 0.87 GAA (1.00) GAAPOLBGFERALDH1A1PKM
SCHEMBL8529006 0.87 POLB (0.69) GAAPOLBGFERALDH1A1PKM
SCHEMBL8047007 0.87 L3MBTL1 (0.68) GAAPOLBGFERALDH1A1PKM
SCHEMBL8057512 0.87 GAA (0.63) GAAPOLBGFERALDH1A1PKM
SCHEMBL8046971 0.87 POLB (0.69) GAAPOLBGFERALDH1A1PKM
SCHEMBL8057506 0.87 GAA (0.63) GAAPOLBGFERALDH1A1PKM
SCHEMBL8057552 0.87 L3MBTL1 (0.68) GAAPOLBGFERALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0706997-B1 Sulfonyl compound and thermal-sensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1998-03-11 EP claimed
EP-0706997-A1 Sulfonyl compound and thermal-sensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1996-04-17 EP claimed
EP-0706997-B1 Sulfonyl compound and thermal-sensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1998-03-11 EP disclosed
US-5705452-A AS DEVELOPER; HIGH SENSITIVITY, LOW BACKGROUND BLUSH DURING STORAGE, RESISTANCE TO HEAT, MOISTURE, PLASTICIZER SANKO HAIHATSU KAGAKU KENKYUSHO (JP) 1998-01-06 US disclosed
EP-0706997-A1 Sulfonyl compound and thermal-sensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1996-04-17 EP disclosed