Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 2/20 | 0.39 |
| ▸ | NPY4R | P50391 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120934 | 0.94 | HTT (0.48) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL8112045 | 0.92 | FOLH1 (0.45) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL8126814 | 0.89 | FOLH1 (0.48) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL8114425 | 0.89 | ATM (0.46) | FOLH1HTTSLC1A3SLC1A1 | |
| SCHEMBL6899868 | 0.86 | NPY1R (0.42) | NPY1RNPY4RNPY5R | |
| SCHEMBL7059809 | 0.86 | NPY1R (0.42) | NPY1RNPY4RNPY5R | |
| SCHEMBL8527836 | 0.85 | NPY1R (0.43) | NPY1RNPY4RNPY5R | |
| SCHEMBL8119315 | 0.84 | NPY1R (0.42) | NPY1RNPY4RNPY5R | |
| SCHEMBL8072950 | 0.83 | FOLH1 (0.46) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL8069648 | 0.83 | FOLH1 (0.44) | FOLH1HTTSLC1A3SLC1A1DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |